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Teridoll
Fri Jun 26 2009, 02:10PM

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I am in hopes someone can shed some light on this subject for me... PLEASE@!!!! I don't know what to do ???
As many of you know... I found a Neo puppy from a breeder in PA (Mike P. from Mastinari's Neopolitan Mastiffs to be exact). My brother also bought one of the litter mates, and I have since learned that another puppy was sold to a lady in Annapolis, MD. Puppies were all doing fine. Annapolis puppy was the first to have be rushed to the emergency clinic for pneumonia... She had been in for cherry eye surgery and spay three days before and nobody saw anything wrong w/ her. Three days later she dropped was running a high fever, lethargic, coughing and congested and white blood cell count down. Then the next week my brother's little girl dropped in almost the same manner! I rushed to his house to see what they were freaking out about... I was not prepared for what I saw. They said she was fine... completely fine about 4 hours earlier that day. Her eye lids were white, her gums where white, even her toe nails were white! She was completely unresponsive ( you could pick up her paw and drop it on the floor and she wouldn't even look at you) she was shaking almost seizure like. They rushed her in to the ER and same thing pneumonia! I received emails from both and of course was on the watchful eye w/ my pup, Nisse. About a week later I noticed an occasional cough here and there from Nisse. I took her in and they told me she had a slight upper respiratory infection. She was put on Clavamox for 14 days... seemed to be doing better.
Annapolis puppy was on antibiotics for 3 weeks! No improvement. Her vet suggested a bacteria wash of the throat, after suggesting lungworm and administering Panacur for 3 days to be retreated in 3 weeks... she goes on Tues for another check up w/ a lung specialist... They have now spent almost $3000 trying to figure out what is wrong w/ this puppy.
Brother's puppy; also on antibiotics for 3 weeks and almost no improvement. Comes and goes. Her vet suggested lungworm and put her on Panacur for 10 days. Panacur treatment done and still a slight cough. Sounds a bit better though...
Nisse was on Clavamox for 14 days... her last dose was Monday... today is friday and she has gotten ALOT worse!!! Took her back to the vet for the 5th time now... saw my third vet from this practice. He suggested that I ask the breeder for a refund and return my puppy!!! (Can I just say WHAT AN "Filtered Word"!) Says he believes it is a congential defect of the throat and that she is aspirating food and/or water into her lungs. Did not suggest putting her back on Clavamox... and told me that I could have a fecal antec test done for lungworms if I really wanted to, but that the chances of it being lungworms was slim to none... even after I informed him that the bitch of this litter was just imported from Norway (I read recently that lungworm is a growing problem in the UK). The other two puppies were not tested for lungworm... just treated as a preventative measure.
So now we have three sick puppies... the OPINION of at least six different vets from different practices... and still no real diagnosis. I think I need to call House@! Has anyone ever heard of such a problem in Neo's??? I can't come up w/ any information regarding throat defects except cleft palate in the breed. PLEASE HELP! This is not a matter of money, as we have collectively spent approx. $5000 to come w/ no results... I just wondered if anyone has ever had a similar problem?


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Phil
Fri Jun 26 2009, 02:32PM
Worlds Biggest "Filtered Word"

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I would definitely speak with the breeder.
He has a site here Click This Link

and has a page entitled ethical neapolitan mastiff breeding program

so it should be worth a try to see what about the other littermates.

someone else more knowledgable may be able to give advice on treatments.
I am in Uk and have never heard tell of lungworms before

Good Luck

Phil

Mastino Napoletano
Neapolitan Mastiff Breeders Uk Ireland


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Witch Hazel
Fri Jun 26 2009, 03:16PM

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I have no suggestions.
I just wanted to send well wishes and say I am so sorry for you and your dogs and everyone involved!
I will watch the thread and please let everyone know what happens.
Sorry!
Cathy

[ Edited Fri Jun 26 2009, 03:17PM ]


"When one tugs at a single thing in nature, he finds it attached to the rest of the world." - John Muir
Cathy Walker
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ccal
Fri Jun 26 2009, 04:05PM

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Never heard of these people but I wish you better luck....... You should contact them as Phil mentioned

[ Edited Fri Jun 26 2009, 04:06PM ]

.
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shellydawn
Fri Jun 26 2009, 04:47PM

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Theresa, have any of the pups been tested for a fungal infection of the lung. Fungal infections can drop your puppy quick. It is treated with antibiotics, but not the same antibiotics as a bacterial infection in the lung. Ketoconazole is one type of antibiotic used to treat this. Some vets use others. I would contact your vet again right away.

Edited for spelling.

[ Edited Fri Jun 26 2009, 05:33PM ]

SHELLY
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Wolf
Fri Jun 26 2009, 05:08PM

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I would definitely speak with the breeder.
He has a site here Click This Link
and has a page entitled ethical neapolitan mastiff breeding program


Lousy website, a lot of jerkoff gibberish and TONS of puppy pics. No thanks.



[ Edited Fri Jun 26 2009, 05:09PM ]

Al Wolf
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Carrie-Ann
Fri Jun 26 2009, 06:47PM

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Could it be bedding eg damp straw/hay or bad food(damp,mouldy) that the breeder used?, ive seen this in ponies, im picking at straws here lmao like mushroom lung/farmers lung or whatever its called, im in uk and havent really heard of lung worm either , i have a import from norway and they are very strict about worming etc, it took a year to get my imports because of all the faffing about.



[ Edited Fri Jun 26 2009, 06:55PM ]

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Joni
Fri Jun 26 2009, 06:55PM

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My first thought was fungal infection also like Shelly said. I would get that ruled out to be on the safe side. I would keep in close contact with the other puppy owners and ask them to keep you updated on what their vets find (It sounds like you are already doing that though). I had a pup arrive off a plane once with severe pneumonia. The pup couldn't even walk and you could hear every breath she took. I rushed her into the vet on a weekend (had to call him in) and he gave her sub Q fluids and Clavamox and within 48 hours the pup seemed almost cured. It sounds like more than pneumonia. Especially considering all three littermates living in different homes came down sick at the same time. I would most definitely contact the breeder and let him know what is going on. Maybe he can be of help or at least let you know if any of the other pups in the litter have had similar problems. Good luck with your puppy and let us know how you make out.

Joni Doten
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Karen
Fri Jun 26 2009, 07:00PM

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Hi Terri,
Really sorry to hear about the pups...

Ok this is is quite complex ... I had a pup who develped an allergy when i started weaning, then he started coughing when he was eating and was a greedy eater (because he was hungry) he developed aspiration pneumonia.

The esophagus is the tube connecting the throat to the stomach. When we eat food is fed into the esophagus, swallowing reflex causes muscle contraction and relaxation which in turn lead to movement of the food into the stomach, other reflexes prevent breathing during this swallowing process to protect the lungs from aspiration.

When these reflexes are interrupted by disease in the esophageal tissue or nerve disease, the esophagus loses its ability to transport food. Instead the esophagus loses all tone and dilates. The reflex protecting the lung is disrupted and aspiration pneumonia commonly follows.

Most cases involve young puppies. These are mostly believed to be congenital, it often show ups when the pup begins to try solid food. Congenital megaesophagus occurs due to incomplete nerve development in the esophagus. The good news is that it may improve as the pup matures.

Hypothyroidism may also be a possible cause of megaesophagus. but megaesophagus does not correct with thyroid replacement therapy, you have to treat that seperately...

megaesophagus can be diagnosed by radiograph. Barium meal is not advisable because of the tendency to inhale or "aspirate" .

If the pup has "aspiration pneumonia" from inhaling regurgitated food material. Chest radiographs in combination with a history of cough, nasal discharge, and the presence of fever indicate pneumonia. Usually the chest radiographs will show disease in the areas of the chest which are lowest in the standing animal as this is where gravity draws inhaled material down.

Aspiration pneumonia makes the case much more serious as pneumonia itself can be life-threatening.

Endoscopy (camera) is an important test for megaesophagus. Ulcers on the esophageal walls will be seen and any narrowings will be obvious. Biopsies can be taken if any suspicious lesions are present.

Also Blood testing to rule in or out treatable causes of megaesophagus...

The first step is to determine if the dog does better with a liquid or solid diet.
Get an elevated bowl, its better if they eat from an elevated position
If the “cardiac sphincter” which separates the stomach from the esophagus is weak, regurgitation may still occur.
Metoclopramide (trade name: Reglan) may help increase the tone of this sphincter.

Medication for nausea may be helpful and strong antacids will help acid damage to the esophagus when food is regurgitated from the stomach.

Cisapride helps reduce episodes of regurgitation

Aspiration pneumonia is treated with fluids and antibiotics as is any other bacterial pneumonia, though these individuals may re-aspirate at any time and require treatment all over again..

It is hard to manage and treatment can be expensive, plus it requires dedication and commitment and may still produce poor results.



Karen
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Karen
Fri Jun 26 2009, 07:05PM

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I am not saying this is the problem, but it is worth ruling out...
Good luck

Karen
'Worry is like a rocking chair, keeps you going but gets you nowhere!'
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Homeward Bound Pet Passport Kennels home of Treloarneo Mastini (France)
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